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FRINGS pilot fermenter PROREACT
for the optimization of fermentation processes
 

FRINGS has developed a new fermentation unit for use in laboratories and biological production processes.

Due to its modular design, the FRINGS Pilot fermenter PROREACT can be custom configured.

It is suitable for a broad range of applications in different processes of blue and white biotechnology, including enzymes, yeasts and bacteria.

  • Special yeast strain fermentations
  • High cell-density fermentations
  • To be used for R&D, as intermediate stage in scale-up processes or as mobile production unit

FRINGS PROREACT is available in sizes ranging from 20 L to 500 L.

 
 
 
 
 

Fig. 1 and 2: Lab fermenter PROREACT 5 G with integrated IPC automation software

 
 
 
 
 

Fig. 2

 

Advantages of PROREACT: 

  • Hygienic design according to QHD standards;
  • Modular design allows for custom configuration;
  • Efficient oxygen transfer ensured by stirring and aeration system; 
  • Mechanical defoaming;
  • Clear reduction of pure culture time of bacteria/yeast strains.



 

Highly efficient aeration fermenter

PROREACT has been designed especially for aerobic fermentations.

The highly efficient aeration system FRIBORATOR achieves particularly high oxygen transfer rates at low energy consumption.

The mechanical foam destruction system FOAMEX P allows you to control the foam formation in the fermenter.

Measurement technology and process control

PROREACT  is equipped with special measurement probes for pH and O2 determination.

The system ALCOSENS 2620 allows for on-line measurement of ethanol or methanol.

Integrated control software converts these measurement signals into feed strategies and control concepts.

  • Electro polished stainless steel vessel with 9 DN15/DN25 ports
  • Hygienic design
  • Use of probes and components for dosage, aeration, sampling, on-line measurement, harvest, foam destruction, CIP, etc.
  • Central connections for inlet and discharge of steam, water, air and waste water
  • Sterile aeration via FRINGS FRIBORATOR with high gas transfer rate
  • Integrated process control with graphic user interface

 
 
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